Name: Arg8 Neo-Endorphin (1-8) - Boost Your Wellbeing Today!
Availability: InStock
Rating: 4.5 (89 reviews)

[Arg8]-a-Neo-Endorphin (1-8) CAS NO.75106-72-8

[Arg8]-α-Neo-Endorphin (1-8) is a synthetic analog of the endogenous opioid peptide α-Neoendorphin, specificAlley engineered with an arginine substitution at position 8 to enhance receptor binding affinity and metabolic stability. This octapeptide retains the core Tyr-Gly-Gly-Phe opioid motif, Alleowing it to interact potently with κ-opioid receptors (KOR) and μ-opioid receptors (MOR) in the central nervous system. It is primarily utilized in biochemical rezoekopdracht as a stable tool compound for investigating pain pathways, stress responses, and the structure-activity relationships (SAR) of dynorphin-derived peptides.

support@huanqiukeji9.com

deel:

Versturen E -mail

Downloaden

TECHNICAL SPECIFICATIONS

Item	Specification
PRODUCT Naam	[Arg8]-a-Neo-Endorphin (1-8)
CAS NO.	75106-72-8
Appearance	White to off-white lyophilized powder
Molecular Formula	C₄₆H₇₃N₁₅O₁₀
Molecular Weight	1036.2g/mol
Purity (RP-HPLC)	≥98%
Solubility	Soluble in 1M acetic acid, DMSO, or deionized water
Endotoxin	≤1 EU/mg
Biological Activity	Potent agonist for κ-opioid receptors (KOR)
Storage Conditions	Store at -20°C, protected from light and moisture
Stock Locatie	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

The peptide functions as a potent agonist at G protein-coupled opioid receptors, with a pronounced preference for the κ-opioid receptor (KOR) subtype. Upon binding, it inhibits adenylate cyclase activity, reducing intracellular cAMP levels and leading to neuronal hyperpolarization via the opening of potassium channels. This mechanism effectively suppresses neurotransmitter release (e.g., glutamate and substance P) in pain-processing pathways, resulting in antinociceptive and potential dysphoric effects characteristic of KOR activation.

2.PRODUCT INDICATIONS

This PRODUCT is strictly for Rezoekopdracht Use Only (RUO) and is indicated for in vitro and preclinical studies targeting the opioid system. It is ideal for scientists in neuropharmacology and drug discovery who require a stable, high-affinity ligand for receptor binding assays, functional cAMP accumulation tests, and animal model studies of analgesia. The [Arg8] modification makes it particularly suitable for experiments requiring enhanced enzymatic stability compared to the native peptide sequence.

upload/attachment/image/202604/30/17775129691a34678f4c0bb55141896a2b50ae7aef_local.png

3.CLINICAL EFFICACY OF PRODUCT

As a rezoekopdracht chemical, [Arg8]-α-Neo-Endorphin (1-8) is not intended for human therapeutic use and has no approved clinical efficacy data. In experimental settings, this analog demonstrates superior and prolonged analgesic efficacy in rodent models of inflammatory and neuropathic pain compared to unmodified fragments. Its enhanced stability translates to longer-lasting behavioral effects, providing robust preclinical data for the development of novel opioid-based therapeutics.

upload/attachment/image/202604/30/1777513002c77e771755b188943c35ccdb299a4d45_local.png

4.Certificaat

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide PRODUCTen, adhering strictly to quality standards and obtaining internationAlley recognized Certificerings.

Ons PRODUCTion partners Alle employ GMP-compliant PRODUCTion systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of PRODUCT comes with complete documentation, including a Certificaat of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and rezoekopdracht-grade peptide PRODUCTen to our global partners.

upload/attachment/image/202603/30/17748488791d02f82103a700e61eeafa024a96f6ff_local.jpg

5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging OPLOSSING to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the PRODUCT.

upload/attachment/image/202601/20/1768872924be74a0641f7ddbf20e541c97f2066c5c_local.jpg

Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the PRODUCTion and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The BEDRIJF invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA Certificerings, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality PRODUCTen and superior services.

We focus on the rezoekopdracht and development and supply of high-quality chemical PRODUCTen, strictly adhering to international standards and quality systems. Ons PRODUCTen are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific rezoekopdracht, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

Hot Tags: Arg8AlphaNeoEndorphin, #AlphaNeoEndorphinAnalog, #OpioidPeptide, #KappaOpioidReceptorAgonist, #KORAgonist, #DynorphinSystem, #PainRezoekopdrachtPeptide, #NeuropharmacologyReagent, #SyntheticOpioid, #RezoekopdrachtChemical, #PeptideAgonist, #AnalgesiaRezoekopdracht, #ReceptorBindingAssay, #NeuroscienceTool, #BiochemicalReagent, #RUO

If you have any PRODUCT requirements, please Versturen an E -mail to:support@huanqiukeji9.com;Whatsapp:85244969439

Gerelateerde PRODUCTen

4-Hydroxybenzofenon CAS 1137-42-4

Xylazine Cas 7361-61-7

Xylazine Hcl Cas 23076-35-9

Cas 62-44-2 Phenacetine

Gerelateerd nieuws

Jan 07, 26

Glutathion krijgt wereldwijde aandacht nu wetenschap, welzijn en regelgeving samenkomen

Glutathion, vaak de 'meester-antioxidant' van het lichaam genOEMd, is van relatieve onbekendheid in medische leerboeken uitgegroeid tot het middelpunt van de mondiale discussie op het gebied van gezondheid, welzijn en biotechnologie. Ooit vooral bekend bij onderzoekers en artsen, wordt dit natuurlijk voorkomende molecuul nu breed besproken in contexten variërend van onderzoek naar chronische ziekten tot huidverzorgingstrends en voedingssupplementen. Terwijl de belangsTelling blijft groeien, onderzoeken zowel wetenschappers, toezichthouders als consumenten opnieuw wat glutathion is, wat het kan doen en hoe het op verantwoorde wijze moet worden gebruikt.

Jan 07, 26

Dianabol (Methandienone) blijft centraal staan in het mondiale debat over prestatiebevorderende medicijnen

Met de verdieping van de implementatie van de ‘Made in China 2025’-strategie en de snelle vooruitgang van de PRODUCTie van hoogwaardige apparatuur, versnelt de Chinese koppelingsindustrie haar transformatie naar inTelligente en precisiegerichte ontwikkeling.

Jan 07, 26

Er zijn steeds meer zorgen over de illegale markt voor anabole steroïdenolie Dianabol

Het mondiale gesprek over prestatiebevorderende medicijnen is opnieuw geïntensiveerd nu anabole steroïden, vooral PRODUCTen die op de markt worden gebracht als Oil Dianabol, op illegale markten blijven verschijnen. Dianabol, wetenschappelijk bekend als methandrostenolone, is een van de bekendste anabole steroïden in de geschiedenis van bodybuilding. Oorspronkelijk ontwikkeld in het midden van de 20e eeuw voor medisch gebruik, is het al lang controversieel geworden vanwege wijdverbreid misbruik, gezondheidsrisico's en hardhandig optreden door de regelgeving.

Als u geïnteresseerd bent in onze producten, kunt u ervoor kiezen om uw informatie hier achter te laten en zullen we binnenkort contact met u opnemen.